Research Education Publication Lab CV and Contact

Publications

13. "Spontaneous transfer of small peripheral peptides between supported lipid bilayer and giant unilamellar vesicles"
Emanuela Efodili, Ashlynn Knight, Maryem Mirza, Cedric Briones, Il-Hyung Lee, Biochimica et Biophysica Acta (BBA) - Biomembranes,, 1866, 2 (2024)

12. "Membrane cargo density-dependent interaction between protein and lipid domains on the giant unilamellar vesicles"
Juan Ureña, Ashlynn Knight, Il-Hyung Lee, Langmuir, 38, 15 (2022): 4702–4712.

  • Read also in CSAM news feed: "Professor and students’ publication supplemental cover of Langmuir"



  • 11. "Intelligent fluorescence image analysis of giant unilamellar vesicles using convolutional neural network"
    Il-Hyung Lee, Sam Passaro, Selin Ozturk, Juan Ureña, Weitian Wang. BMC Bioinformatics 23, 48 (2022).

    10. "Lipid raft phase modulation by membrane-anchored proteins with inherent phase separation properties"
    Il-Hyung Lee, Matthew Y. Imanaka, Emmi H. Modahl, Ana P. Torres-Ocampo. ACS Omega, 4, no. 4 (2019): 6551-6559.

    Underlined authors above are student authors from the Lee group.

    9. "ATP-dependent force generation and membrane scission by ESCRT-III and Vps4"
    Johannes Schöneberg, Mark Remec Pavlin, Shannon Yan, Maurizio Righini, Il-Hyung Lee, Lars-Anders Carlson, Amir Houshang Bahrami, Daniel H Goldman, Xuefeng Ren, Gerhard Hummer, Carlos Bustamante, James Hurley. Science, 362, no. 6421 (2018): 1423-1428.

    8. "Reverse-topology membrane scission by the ESCRT proteins."
    Johannes Schöneberg*, Il-Hyung Lee*, Janet H. Iwasa, and James H. Hurley. Nature Reviews Molecular Cell Biology 18, no. 1 (2017): 5-17.

    7. "Negative membrane curvature catalyzes nucleation of endosomal sorting complex required for transport (ESCRT)-III assembly." 
    Il-Hyung Lee, Hiroyuki Kai, Lars-Anders Carlson, Jay T. Groves, and James H. Hurley. Proceedings of the National Academy of Sciences 112, no. 52 (2015): 15892-15897.

    6. "Diffusion of GPI-anchored proteins is influenced by the activity of dynamic cortical actin."
    Suvrajit Saha, Il-Hyung Lee, Anirban Polley, Jay T. Groves, Madan Rao, and Satyajit Mayor. Molecular biology of the cell 26, no. 22 (2015): 4033-4045.

    5. "HIV-1 Nef hijacks clathrin coats by stabilizing AP-1: Arf1 polygons."
    Qing-Tao Shen, Xuefeng Ren, Rui Zhang, Il-Hyung Lee, and James H. Hurley. Science 350, no. 6259 (2015): aac5137.

    4. "Solution structure of the Atg1 complex: implications for the architecture of the phagophore assembly site."
    Jürgen Köfinger, Michael J. Ragusa, Il-Hyung Lee, Gerhard Hummer, and James H. Hurley.  Structure 23, no. 5 (2015): 809-818.

    3. "Live cell plasma membranes do not exhibit a miscibility phase transition over a wide range of temperatures." 
    Il-Hyung Lee, Suvrajit Saha, Anirban Polley, Hector Huang, Satyajit Mayor, Madan Rao, and Jay T. Groves. The journal of physical chemistry B 119, no. 12 (2015): 4450-4459.

    2. "Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity."
    Margaret Stratton*, Il-Hyung Lee*, Moitrayee Bhattacharyya, Sune M. Christensen, Luke H. Chao, Howard Schulman, Jay T. Groves, and John Kuriyan. eLife 3 (2014): e01610.

    1. "A mechanism for tunable autoinhibition in the structure of a human Ca 2+/calmodulin-dependent kinase II holoenzyme."
    Luke H. Chao, Margaret M. Stratton, Il-Hyung Lee, Oren S. Rosenberg, Joshua Levitz, Daniel J. Mandell, Tanja Kortemme, Jay T. Groves, Howard Schulman, and John Kuriyan. Cell 146, no. 5 (2011): 732-745.

    Recent presentations by the principal investigator

    [Talk]. "Deep-learning applications in the automated image analysis of giant unilamellar vesicles."
    Il-Hyung Lee, Weitian Wang, 67th Biophysical Society Annual Meeting , San Diego, CA. (Feb, 2023)

    [Talk]. "Interaction between lipid domains and protein domains on the reconstituted model membrane systems."
    Il-Hyung Lee, Juan Ureña, Ashlynn Knight, ACS Spring 2022, San Diego, CA. (Mar, 2022)